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Frontotemporal dementia and parkinsonism linked to chromosome 17
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Frontotemporal dementia and parkinsonism linked to chromosome 17 : ウィキペディア英語版
Frontotemporal dementia and parkinsonism linked to chromosome 17
Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) is an autosomal dominant neurodegenerative disorder and Parkinson plus syndrome, which has three cardinal features: behavioral and personality changes, cognitive impairment, and motor symptoms. FTDP-17 was defined during the ''International Consensus Conference in Ann Arbor'', Michigan, in 1996.
==Pathophysiology==
The pathogenetic mechanisms underlying the disorder are thought to be related to the altered proportion of tau isoforms or to the ability of tau to bind microtubules and to promote microtubule assembly.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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